CAS： 137-58-6
MF： C14H22N2O
Appearance： solid
| Defintion | Lidocaine (CAS 137-58-6) is a local anesthetic and antiarrhythmic agent commonly used to numb tissue or treat ventricular arrhythmias. |
| Uses | Lidocaine (LIDO) was discovered in the 1940s by Nils Lofgren and Bengt Lundquist and it is one of the most popular drugs. This drug is an amide anesthetic used for local anesthetic procedures. It was initially used intravenously as an antiarrhythmic agent. It was later proposed that intravenous LIDO had an analgesic effect that could potentially be beneficial in perioperative settings. Since then, LIDO has been a local anesthetic and antiarrhythmic widely used in several areas of medical practice. |
| Purification Methods | Lidocaine (CAS 137-58-6) can be purified by dissolving it in a suitable solvent like ether or chloroform, followed by extraction with dilute acid to form the hydrochloride salt. This salt can be recrystallized from ethanol or water. Another common method involves recrystallizing the free base from anhydrous acetone. Additionally, impurities can be removed by washing with water and then drying under vacuum to yield purified lidocaine. |
| Reference |
A Review of the Lidocaine in the Perioperative Period [J. Pers. Med. 2023, 13(12), 1699;] Lidocaine: The Origin of a Modern Local Anesthetic [Anesthesiology December 2010, Vol. 113, 1433–1437.] |
Hebei KuiSheng Trading Co., LTD is a newly established company specializing in the production and supply of high-quality chemicals for a variety of sectors, including pharmaceutical, agricultural, and industrial applications. Through advanced technology and strict quality control, the company ensures that its products meet rigorous standards for performance, efficiency, and safety. Hebei KuiSheng is committed to competitive pricing, offering chemicals with purities exceeding 99% and maintaining a robust inventory for quick fulfillment of orders of any size. As a manufacturer, the company can provide factory prices and reliable logistics for fast, secure deliveries, with OEM services available to meet specific customer needs. Hebei KuiSheng has swiftly established a solid distribution network, improved product quality, and expanded into international markets, where it continues to build its reputation through customer satisfaction and long-lasting business relationships based on trust and mutual success.
