CAS： 50-28-2
MF： C18H24O2
Appearance： white crystalline powder
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β-ESTRADIOL is white crystalline powder, while it's Molecular Formula is C18H24O2.
The CAS number of β-ESTRADIOL is 50-28-2.
β-Estradiol (17β-estradiol) is a potent form of estrogen, the primary female sex hormone, and plays a key role in regulating reproductive and sexual functions. It is used therapeutically in hormone replacement therapy (HRT) for menopausal women to alleviate symptoms such as hot flashes, mood swings, and vaginal dryness. It is also used in treating conditions like osteoporosis, where it helps maintain bone density, and in gender-affirming hormone therapy for transgender women. β-Estradiol is commonly found in birth control pills and is prescribed for menstrual disorders or ovarian function issues. Additionally, it has applications in research as a hormone assay standard.
InChI:InChI=1/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m0/s1
Articles related to β-ESTRADIOL:
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Article |
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| Regulation of MCF-7 Breast Cancer Cell Growth by β-estradiol Sulfation |
Metabolism of β-estradiol (E2), the major endogenous human estrogen, is important in regulating both the level and activity of the hormone in breast tissues. Conjugation of E2 with a sulfonate moiety is an inactivation process since the sulfate ester formed by this reaction can not bind and activate the estrogen receptor. Josie L. Falany, Nancy Macrina & Charles N. Falany , Breast Cancer Research and Treatment, Volume 74, pages 167–176, (2002) |
| β-Estradiol and ethinyl-estradiol contamination in the rivers of the Carpathian Basin |
17β-Estradiol (E2) and 17α-ethinyl estradiol (EE2), which are environmental estrogens, have been determined with LC-MS in freshwater. Their sensitive analysis needs derivatization and therefore is very hard to achieve in multiresidue screening. We analyzed samples from all the large and some small rivers (River Danube, Drava, Mur, Sava, Tisza, and Zala) of the Carpathian Basin and from Lake Balaton. Péter Avar, Zita Zrínyi, Gábor Maász, Anikó Takátsy, Sándor Lovas, László G.-Tóth & Zsolt Pirger , Environmental Science and Pollution Research, Volume 23, pages 11630–11638, (2016) |
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