CAS： 10009-20-8
MF： C8H13F3N2O3
|
Definition |
ChEBI: An N6-acyl-L-lysine where the N6-acyl group is trifluoroacetyl. |
| Description | N6-Trifluoroacetyl-L-lysine is a derivative of lysine that is used in peptide synthesis. It protects lysine from oxidation during peptide synthesis and helps form bonds between amino acids. |
| Uses | N-6-Trifluoroacetyl-L-lysine N-carboxyanhydride is used to form bonds between amino acids and protect lysine from oxidation during peptide synthesis. |
InChI:InChI=1/C8H13F3N2O3/c9-8(10,11)7(16)13-4-2-1-3-5(12)6(14)15/h5H,1-4,12H2,(H,13,16)(H,14,15)/t5-/m0/s1
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Each enantiomer of N-chloroacetyltyrosine was reassigned to the initiation AUG codon. (c)Selection of cyclic peptides containing N-6-trifluoroacetyl-L lysine against sirtuin 2 (SIRT2). Each enantiomer of N-chloroacetyl-tyrosine was reassigned to the initiation AUG codon and N-6-trifluoroacetyl-L-lysine ( CF3K) was reassigned to the elongation AUG codon.
Lysyl oxidase (LOX) is implicated in sev...
Methods of treatment and substances for ...
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S-ethyl trifluoroacetate
L-Lysine hydrochloride
(S)-6-trifluoroacetylamino-2-aminohexanoic acid
| Conditions | Yield |
|---|---|
|
With sodium hydroxide;
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ethyl trifluoroacetate,
L-Lysine hydrochloride
(S)-6-trifluoroacetylamino-2-aminohexanoic acid
| Conditions | Yield |
|---|---|
|
With sodium; In ethanol; at 5 - 20 ℃;
|
62% |
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L-Lysine hydrochloride; With ethanol; sodium;
ethyl trifluoroacetate,; In ethanol; at 20 ℃; Cooling with ice;
With acetic acid; In ethanol;
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62% |
|
L-Lysine hydrochloride; With sodium; In ethanol; for 1h;
ethyl trifluoroacetate,; at 5 - 20 ℃; for 3h;
With acetic acid; for 0.166667h;
|
56% |
S-ethyl trifluoroacetate
L-Lysine hydrochloride
ethyl trifluoroacetate,
sodium salt of L-lysine
(2S)-2-{[(benzyloxy)carbonyl]amino}-6-[(trifluoroacetyl)amino]hexanoic acid
Nε-trifluoroacetyl-L-lysine Nα-carboxanhydride
C9H11Cl2F3N2O3
Nα-(o-nitrophenylsulfenyl)-Nε-(trifluoroacetyl)lysine
