CAS： 58-33-3
MF： C17H20N2S.HCl
Appearance： white to faint yellow crystalline powder
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Promethazine hydrochloride is white to faint yellow crystalline powder, while it's Molecular Formula is C17H20N2S.HCl. Promethazine hydrochloride is used as antihistamine; antiemetic; central nervous system depressant; sedative; anticholinergic; antiserotoninergic; local anesthetic; in the treatment of motion sickness, cough linctuses, nausea, and allergic conditions; used to control Parkinsonian symptoms and as central nervous system depressant; in pills, syrup, injections and suppositories.
The CAS number of Promethazine hydrochloride is 58-33-3.
More information of Promethazine hydrochloride 58-33-3 are:
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Synonyms |
Phenothiazine, 10-[2-(dimethylamino)propyl]-, monohydrochloride (8CI);10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride;Anergan 25;Diprazin;Dorme;Fenazil;Genphen;Himazin;Lergigan;Mepergan;NSC 231688;PhanerganD;Phencen;Phenergan;Phenergan VC;Plletia;Promasun;Prorex;Provigan;Pyrethia;Romergan; |
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CAS Number |
58-33-3 |
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Molecular Formula |
C17H20N2S.HCl |
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Molecular Weight |
320.886 |
|
Density |
1.131 g/cm3 |
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Melting Point |
230-232°C |
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Boiling Point |
403.7 °C at 760 mmHg |
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Flash Point |
198 °C |
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HS CODE |
29343000 |
|
PSA |
31.78000 |
|
LogP |
5.10640 |
Promethazine hydrochloride is a medication used to manage and treat allergic conditions, nausea and vomiting, motion sickness, and sedation. Promethazine also has off-label uses for nausea and vomiting in pregnancy. Promethazine hydrochloride is a phenothiazine derivative with antidopaminergic, antihistamine, and anticholinergic properties. If you take it for insomnia or take it at bedtime, promethazine will help you sleep. If you take it during the day for other conditions, such as allergies, it might make you feel sleepy during the day as well.
InChI:InChI=1/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H/p-1
Articles related to Promethazine hydrochloride:
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Article |
Source |
| Voltammetric determination of chlorpromazine hydrochloride and promethazine hydrochloride with the use of multivariate calibration |
The voltammetric behavior of antipsychotic drugs, such as, chlorpromazine hydrochloride and promethazine hydrochloride has been investigated at a glassy carbon electrode in Britton–Robinson buffer of pH 9. It was found by applying the differential pulse stripping voltammetry (DPSV) that both chlorpromazine hydrochloride and promethazine hydrochloride had well formed oxidation voltammetric waves, with the peak potential for chlorpromazine hydrochloride at 620 mV, and for the two peaks of promethazine hydrochloride at 444 and 668 mV. , Yongnian Ni a , Li Wang a , Serge Kokot b , Analytica Chimica Acta Volume 439, Issue 1, 17 July 2001, Pages 159-168 |
| Study on the interaction between promethazine hydrochloride and bovine serum albumin by fluorescence spectroscopy |
The interaction between promethazine hydrochloride (PMT) and bovine serum albumin (BSA) in vitro was investigated by means of fluorescence spectroscopy and absorption spectroscopy. The fluorescence of BSA was quenched remarkably by PMT and the quenching mechanism was considered as static quenching by forming a complex. , Lingling He a b , Xin Wang c , Bin Liu a c , Jun Wang c , Yaguang Sun b , Enjun Gao b , Shukun Xu a , Journal of Luminescence Volume 131, Issue 2, February 2011, Pages 285-290 |
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