Madecassoside

Base Information

  • PRODUCT:Madecassoside
  • CAS.:34540-22-2
  • MF:C48H78O20
  • Molecular Weight:975.12
  • Purity:99%

Product Details

CAS: 34540-22-2

MF: C48H78O20

Appearance: Powder

Perfect Factory Offer Excellent quality Madecassoside 34540-22-2 with Safe Shipping

  • Molecular Formula:C48H78O20
  • Molecular Weight:975.12
  • Appearance/Colour:Powder 
  • Vapor Pressure:0mmHg at 25°C 
  • Melting Point:220-223 °C 
  • Refractive Index:1.637 
  • Boiling Point:1043.554 °C at 760 mmHg 
  • PKA:12.50±0.70(Predicted) 
  • Flash Point:295.795 °C 
  • PSA:335.44000 
  • Density:1.473 g/cm3 
  • LogP:-2.06200 

Madecassoside(Cas 34540-22-2) Usage

Definition

ChEBI: A triterpenoid saponin that is a trisaccharide derivative of madecassic acid. Isolated from Centella asiatica, it exhibits anti-inflammatory, antioxidant and antirheumatic activities.

Description Madecassoside is a water-soluble ingredient found in the Centella asiatica plant, also known as tiger grass or gotu kola. It's a purified, active form of the plant extract that's used in skincare products for its many benefits.
Uses Madecassoside can help soothe irritated and red skin, and is particularly beneficial for sensitive or acne-prone skin. Madecassoside can help promote wound healing and tissue regeneration. Some studies recommend using this product in the morning or evening. 24% of routines created by our community use it in both the morning and evening.

InChI:InChI=1/C48H78O20/c1-19-10-11-48(13-12-46(6)22(28(48)20(19)2)8-9-27-44(4)14-24(52)39(61)45(5,18-50)38(44)23(51)15-47(27,46)7)43(62)68-42-35(59)32(56)30(54)26(66-42)17-63-40-36(60)33(57)37(25(16-49)65-40)67-41-34(58)31(55)29(53)21(3)64-41/h8,19-21,23-42,49-61H,9-18H2,1-7H3

 

Hebei KuiSheng Trading Co., LTD ,a company specializing in the production and supply of chemicals for various industries. we take pride in our ability to carefully formulate chemicals that meet the highest standards of quality, efficiency, and safety. Through advanced technology and strict quality control measures, we ensure that our products consistently deliver exceptional performance and reliability. Whether you are in need of chemicals for pharmaceutical, agricultural, or industrial applications, we offer a wide range of solutions to meet your specific requirements.

 

In May 2024 —while seeking to expand the international market, we successfully entered some overseas markets. The company has made breakthrough progress in the international market. This brings more opportunities and challenges for the company as well as higher sales and profit margins, and also enhances the company's reputation in the international market.
In April 2024 —it established a solid channel network and continuously improved product quality and service level to adapt to the needs of different countries and regions and improve customer satisfaction.
In March 2024 —our company began to expand the market, improve services, develop target markets and attract customers.
At the beginning of 2024 —Hebei Kuisheng Trading Co., Ltd. was officially established and put into operation.

 

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Madecassoside 34540-22-2 Relevant articles

Actions and Therapeutic Potential of Madecassoside and Other Major Constituents of Centella asiatica: A Review

Swee Ching Tan 1,Subrat Kumar Bhattamisra 2,Dinesh Kumar Chellappan 2, andMayuren Candasamy 2,*

, Appl. Sci. 2021, 11(18), 8475;

Treatment of HGF-induced hepatocellular carcinoma (HCC) cell lines (HepG2 and SMMC-77 cells) with madecassoside significantly reduced HGF-induced proliferative and invasive responses. These effects of madecassoside were associated with the downregulation of the expression of COX-2 and PGE2, and inhibition of p-cMET, p-ERK1/2 and PKC activity.

Madecassoside Inhibits Body Weight Gain via Modulating SIRT1-AMPK Signaling Pathway and Activating Genes Related to Thermogenesis

Boju Sun1, Misa Hayashi, Maya Kudo2, Lili Wu3, Lingling Qin4, Ming Gao,*, Tonghua Liu

, Front. Endocrinol. 12:627950.

Pre-clinical research studies have shown that Madecassoside (MA) has favorable therapeutic effects on arthritis, acne, vitiligo and other diseases. However, the effects of MA on obesity have not yet been studied. This study mainly aimed to investigate the effects of MA in protecting against obesity and its underlying mechanism in reducing obesity.

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