Trimethyl-pyrazine

Base Information

  • PRODUCT:Trimethyl-pyrazine
  • CAS.:14667-55-1
  • MF:C7H10N2
  • Molecular Weight:122.17
  • Purity:99%

Product Details

CAS: 14667-55-1

MF: C7H10N2

Appearance: clear yellow liquid

Offer Chemical Raw Material Trimethyl-pyrazine 14667-55-1 In Stock

  • Molecular Formula:C7H10N2
  • Molecular Weight:122.17
  • Appearance/Colour:clear yellow liquid 
  • Vapor Pressure:1.72mmHg at 25°C 
  • Melting Point:156 °C 
  • Refractive Index:n20/D 1.5040(lit.)  
  • Boiling Point:173.1 °C at 760 mmHg 
  • PKA:2.69±0.10(Predicted) 
  • Flash Point:54.4 °C 
  • PSA:25.78000 
  • Density:0.979 g/cm3 
  • LogP:1.40180 

Trimethyl-pyrazine(Cas 14667-55-1) Usage

Description Trimethyl-pyrazine is present in brown cheese. It is one of the most broadly used edible synthesis fragrances. It comes from baked food, fried barley, potatoes, and peanuts. 2,3,5-Trimethylpyrazine is used for the flavor in cocoa, coffee, chocolate, potato, cereal, and fried nuts.

Aroma threshold values

Detection: 400 ppb to 9 ppm (9 ppm in water)

Taste threshold values

Taste characteristics at 80 ppm: raw, musty, nutty and potato.

Uses

 

Trimethyl-pyrazine, as a volatile heterocyclic nitrogen compound, has a wide range of applications.

Safety Profile

Moderately toxic by ingestion. Combustible liquid. When heated to decomposition emits toxic fumes of NOx.

InChI:InChI=1/C7H10N2/c1-5-4-8-6(2)7(3)9-5/h4H,1-3H3

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14667-55-1 Relevant articles

Optimization of Fermentation Conditions for Trimethyl-pyrazine Produced by Bacillus amyloliquefaciens from Daqu

Xun Liu 1,*,†,Weijie Yang 1,†,Hongyi Gu 1,Ayaz Ali Bughio 1 andJun Liu 1,2,3,*ORCID

, Fermentation 2024, 10(2), 112;

Trimethyl-pyrazine (TMP) is a high-grade spice that has gradually developed in recent years, with a strong aroma of roasted peanuts or potatoes [3]. The specific structural formula of TMP is shown in Figure 1. Trimethyl-pyrazine is common in heated foods, like baked goods, roasted meat, coffee, peanuts, or popcorn, and is mainly formed by the Maillard reaction during food production [4].

Comparison of pyrazines formation in methionine/glucose and corresponding Amadori rearrangement product model

Cui, Heping,Deng, Shibin,Hayat, Khizar,Ho, Chi-Tang,Zhai, Yun,Zhang, Qiang,Zhang, Xiaoming

, (2022/03/07)

The generation of pyrazines in a binary ...

An Alkylpyrazine Synthesis Mechanism Involving l-Threonine-3-Dehydrogenase Describes the Production of 2,5-Dimethylpyrazine and Trimethyl-pyrazine by Bacillus subtilis

Lijie Zhang, Yanli Cao, Jianan Tong, Yan Xu

, Applied and Environmental Microbiology Vol. 85, No. 24

Alkylpyrazines are important contributors to the flavor of traditional fermented foods. Here, we studied the synthesis mechanisms of 2,5-dimethylpyrazine (2,5-DMP) and Trimethyl-pyrazine. The synthesis mechanism described here can also explain the production of Trimethyl-pyrazine. The results provide insights into an alkylpyrazine’s synthesis pathway involving l-threonine-3-dehydrogenase as the catalytic enzyme and l-threonine as the substrate.

14667-55-1 Process route

3-amino-2-propanol
78-96-6,1674-56-2

3-amino-2-propanol

1,4-pyrazine
290-37-9

1,4-pyrazine

2-Methylpyrazine
109-08-0

2-Methylpyrazine

2,5-dimethyl-pyrazine
123-32-0

2,5-dimethyl-pyrazine

2-ethyl-3,6-dimethylpyrazine
13360-65-1

2-ethyl-3,6-dimethylpyrazine

2,3,5-trimethylpyrazine
14667-55-1

2,3,5-trimethylpyrazine

1-aminoethyl-2-methylaziridine

1-aminoethyl-2-methylaziridine

Conditions
Conditions Yield
With copper chromite; at 180 ℃; for 0.333333h; Product distribution; var. temp.; other aminoalcohols;
 
D-glucose
50-99-7

D-glucose

H-Lys-Lys-OH hydrochloride
134276-45-2

H-Lys-Lys-OH hydrochloride

1,4-pyrazine
290-37-9

1,4-pyrazine

2-Methylpyrazine
109-08-0

2-Methylpyrazine

2,5-dimethyl-pyrazine
123-32-0

2,5-dimethyl-pyrazine

2,3-dimethylpyrazine
5910-89-4

2,3-dimethylpyrazine

2-ethyl-3,6-dimethylpyrazine
13360-65-1

2-ethyl-3,6-dimethylpyrazine

2,6-dimethylpyrazine
108-50-9

2,6-dimethylpyrazine

2,3,5-trimethylpyrazine
14667-55-1

2,3,5-trimethylpyrazine

3-ethenyl-2,5-dimethylpyrazine
80935-98-4

3-ethenyl-2,5-dimethylpyrazine

2-ethyl-6-methylpyrazine
13925-03-6

2-ethyl-6-methylpyrazine

Conditions
Conditions Yield
In water; at 130 ℃; for 2h; pH=8;
 

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14667-55-1 Downstream products

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    1,3,7-Trimethyl-pyrrolo[1,2-a]pyrazine

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