CAS: 3081-61-6
MF: C7H14N2O3
Appearance: White crystalline solid
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L-Theanine is White crystalline solid, while it's Molecular Formula is C7H14N2O3. Research suggests L-theanine may have significant anti-stress effects, especially in high-stress situations. In controlled trials, L-theanine has been shown to reduce heart rate and salivary immunoglobulin A responses, markers associated with stress. This reduction in stress response is attributed to a decrease in sympathetic nervous system activation, promoting a state of relaxation. When combined with caffeine, as often occurs naturally in tea, L-theanine may help counterbalance caffeine's stimulatory effects, enhancing cognitive performance, alertness, and mood without the typical jittery side effects. These effects position L-theanine as a beneficial supplement for individuals seeking a calm, focused state of mind, and it continues to be explored for its potential in managing stress and supporting overall mental well-being.
The CAS number of L-Theanine is 3081-61-6.
More information of L-Theanine 3081-61-6 are:
Synonyms |
Glutamine,N-ethyl-, L- (6CI,7CI,8CI);NSC 21308;Ng-Ethyl-L-glutamine;Suntheanine;Theanin;Theanine;L-Theanine (Ngamma-ethyl-L-glutamine); |
CAS Number |
3081-61-6 |
Molecular Formula |
C7H14N2O3 |
Molecular Weight |
174.2 |
Density |
1.171 g/cm3 |
Melting Point |
207 °C |
Boiling Point |
430.2 °C at 760 mmHg |
Flash Point |
214 °C |
HS CODE |
29241990 |
PSA |
92.42000 |
LogP |
0.40580 |
Pka |
2.24±0.10(Predicted) |
L-Theanine is a unique amino acid primarily found in the leaves of Camellia sinensis, the tea plant. Structurally similar to the neurotransmitter glutamate, L-theanine binds to glutamate receptors, exerting a balancing influence on excitatory brain activity. Studies show that it can modulate glutamate receptors such as AMPA, NMDA, and kainate subtypes, resulting in neuroprotective effects. Additionally, L-theanine may increase levels of mood-enhancing neurotransmitters like dopamine, serotonin, and GABA, along with factors that support neuron health, including nerve growth factor and brain-derived neurotrophic factor. These properties make it a valuable compound for promoting relaxation without causing drowsiness, supporting cognitive function, and potentially offering protective benefits against stress-related brain damage.
InChI:InChI=1/C7H14N2O3/c1-2-9-6(10)4-3-5(8)7(11)12/h5H,2-4,8H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1
Articles related to L-Theanine:
Article |
Source |
l-Theanine reduces psychological and physiological stress responses |
The main findings in this study were that the acute stress responses elicited by the mental arithmetic task were reduced by the oral administration of l-Theanine. Moreover, this effect of l-Theanine was consistently observed not only in the subjective perception of stress but also in physiological stress responses such as HR and s-IgA. Although there is a possibility that the buffering effect was induced by a placebo effect, as is frequently seen in clinical trials of medicine. , Kenta Kimura a , Makoto Ozeki b , Lekh Raj Juneja b , Hideki Ohira a , Biological Psychology Volume 74, Issue 1, January 2007, Pages 39-45 |
The effects of l-theanine, caffeine and their combination on cognition and mood |
Clearly further research is needed to explore the cognitive effects of l-theanine and to clarify some of the mood effects. Given the evidence from animal studies for an interaction between caffeine and l-theanine, and the fact that the vast majority of l-theanine consumption is in the form of tea, it is important to assess the effects of l-theanine alone and in combination with caffeine. There was also a significant positive caffeine × l-theanine interaction on delayed word recognition reaction time. These results suggest that beverages containing l-theanine and caffeine may have a different pharmacological profile to those containing caffeine alone. , Crystal F. Haskell a , David O. Kennedy a , Anthea L. Milne a , Keith A. Wesnes a b , Andrew B. Scholey a , Biological Psychology Volume 77, Issue 2, February 2008, Pages 113-122 |
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