CAS： 50-02-2
MF： C22H29FO5
Appearance： White crystalline solid
Buy Good Quality Dexamethasone 50-02-2 with a minimum purity of 99% We supply high quality Dexamethasone (CAS 50-02-2), in stock, factory directly supply to clients, lower prices, more competitiveness.
Dexamethasone is White crystalline solid, while it's Molecular Formula is C22H29FO5. Anti-inflammatory glucocorticoidDexamethasone is used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis and bronchospasm. It is useful to study apoptosis, cell signaling pathways and gene expression. It is associated with marbofloxacin and clotrimazole and finds application in veterinary medicine to treat difficult ear infections in dogs. It is also used to treat horses with swelling of of distal limbs and general bruising in combination with trichlormethiazide. It is also an anti-inflammatory glucocorticoid.
The CAS number of Dexamethasone is 50-02-2.
More information of Dexamethasone 50-02-2 are:
|
Synonyms |
Diodex;Etacortilen;Fluormone;Fluorocort;Gammacorten;HL-Dex;Hexadecadrol;Hexadrol;Isopto-Dex;Loverine;Luxazone;Millicorten;Oradexon;Pet-Derm III;Prednisolone F;Superprednol;Surodex;Visumetazone;Pregna-1,4-diene-3,20-dione,9-fluoro-11,17,21-trihydroxy-16-methyl-, (11b,16a)-;Pregna-1,4-diene-3,20-dione,9-fluoro-11b,17,21-trihydroxy-16a-methyl- (6CI,8CI);1-Dehydro-16a-methyl-9a-fluorohydrocortisone;16a-Methyl-9a-fluoro-D1-hydrocortisone;16a-Methyl-9a-fluoroprednisolone;9-Fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione;9a-Fluoro-16a-methyl-1,4-pregnadiene-11b,17a,21-triol-3,20-dione;9a-Fluoro-16a-methyl-11b,17,21-trihydroxypregna-1,4-diene-3,20-dione;9a-Fluoro-16a-methylprednisolone;Adexone;Aeroseb-Dex;Aphtasolon;Aphthasolone;Azium;Calonat;Corsone;Decacort;Decaderm;Decadron;Decadron A;Dekort;Delipos;Dergramin;Desameton;Dexa-Cortidelt;Dexa-Scheroson;Dexacortin;Dexalona;Dexamethasone alcohol;Dexapolcort;Dexaprol;Dexason;Dexinoral;Dexmethsone;Dexonium;Dinormon; |
|
CAS Number |
50-02-2 |
|
Molecular Formula |
C22H29FO5 |
|
Molecular Weight |
392.468 |
|
Density |
1.32 g/cm3 |
|
Melting Point |
262-264 °C(lit.) |
|
Boiling Point |
568.2 °C at 760 mmHg |
|
Flash Point |
297.5 °C |
|
HS CODE |
HASONE DISODIUM PHOSPHATE PRODUCT IDENTIFICATION |
|
PSA |
94.83000 |
|
LogP |
1.89570 |
|
Pka |
12.13±0.70(Predicted) |
The activity of dexamethasone, as measured by glycogen deposition, is 20 times greater than that of hydrocortisone. It has five times the anti-inflammatory activity of prednisolone. Clinical data indicate that this compound has seven times the antirheumatic potency of prednisolone. It is roughly 30 times more potent than hydrocortisone. Its pharmacokinetics are presented in Table 33.3. Routes of metabolism for dexamethasone are similar to those for prednisolone, with its primary 6β-hydroxy metabolite being recovered in urine. Dexamethasone sodium phosphate is the water-soluble sodium salt of the 21-phosphate ester, with an IV half-life of less than 10 minutes because of rapid hydrolysis by plasma phosphatases. Peak plasma levels for dexamethasone usually are attained in approximately 10 to 20 minutes following its IV administered dose. A similar reaction occurs when the phosphate ester is applied topically or by inhalation.
InChI:InChI=1/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15?,16+,17+,19+,20+,21+,22+/m1/s1
Articles related to Dexamethasone:
|
Article |
Source |
|
Antigen-Drug Conjugates as a Novel Therapeutic Class for the Treatment of Antigen-Specific Autoimmune Disorders |
Pickens, Chad J.,Christopher, Matthew A.,Leon, Martin A.,Pressnall, Melissa M.,Johnson, Stephanie N.,Thati, Sharadvi,Sullivan, Bradley P.,Berkland, Cory , p. 2452 - 2461 (2019) |
|
Method for recycling betamethasone or dexamethasone synthetic mother liquor materials |
- , (2020/03/12) |
Hebei KuiSheng Trading Co., LTD is a quality supplier and manufacturer of Dexamethasone . You can buy high quality, low price Dexamethasone 50-02-2 here. Contact us.
