Dextran Sulfate Sodium Salt

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What is the Dextran Sulfate Sodium Salt ?

Dextran Sulfate Sodium Salt is powder, while it's Molecular Formula is (C6H7Na3O14S3)n. Dextran sulfate sodium salt Leuconostoc spp has been used:as a standard to perform polyacrylamide-gel electrophoresis for carbohydrates (C-PAGE)(59) and agarose gel electrophoresis(60)for RNA sequential probing of targets (SPOTs) imaging(61)as a component of 1% injection buffer(62)

What is the CAS number for Dextran Sulfate Sodium Salt ?

The CAS number of Dextran Sulfate Sodium Salt is 9011-18-1.

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What is Dextran Sulfate Sodium Salt (9011-18-1) used for?

Dextran sulfate (dextran hydrogen sulfate, sodium salt) has been tested as a potential substitute for heparin in anticoagulant therapy. Following studies by Ingelman, Walton and Ricketts explored the anticoagulant properties of a wide range of dextran sulfates (Mw 7000 to 458000) and established that the lowest molecular weight products displayed the highest anticoagulant properties. However, at best this only represented 15% of heparin's activity. With the introduction of low-dose heparin therapy for thrombosis prophylaxis in the 70's, interest in low molecular weight polyanions has been rekindled and reports on interactions with individual enzyme/inhibitor systems in the coagulation cascade have appeared. Dextran sulfate immobilized on cellulose has been found to remove LDL cholesterol preferentially during plasmaphoresis. Its wide spectrum of biological properties has attracted the attention of many scientists. The reports may be grouped according to the following biological effects. Enzyme inhibition, activation and release Adjuvant effect on immune response Cellular interactions and response Effect on virus infectivity

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